As you might guess from the title, Loi’s claim is that the displacement of human workers by machines could lead to widespread human disenhancement. This is due to the differential impact of technological unemployment on the mass of human workers: some will find that technology has an enhancing effect, but most will not.
This is supported largely, though not entirely, by the work of the economist David Autor. Autor is famous for describing the polarisation effect that technology is having on the workforce. In essence, Loi’s argument is that this polarisation effect is likely to result in disenhancement.